Genome-wide gene-smoking interaction study identified novel susceptibility loci for non-small cell lung cancer in Chinese populations - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34297049/
Gene-smoking interactions play important roles in the development of non-small cell lung cancer (NSCLC). To identify single nucleotide polymorphisms (SNPs) that modify the association of smoking behavior with NSCLC risk,...
Circular RNA circβ-catenin aggravates the malignant phenotype of non-small-cell lung cancer via encoding a peptide - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34296778/
doi: 10.1002/jcla.23900. Online ahead of print. 1 Department of Thoracic Surgery, Ningbo First Hospital, Ningbo, China. 2 Department of Thoracic Surgery, The Affiliated Hospital of Medical School, Ningbo University, Ningbo,...
Frontline pembrolizumab for the treatment of RET-rearranged non-small cell lung cancer: A case report - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34166867/
RET-rearrangement occurs in 1 to 2% of patients with non-small cell lung cancer (NSCLC), typically among non-smokers, and it is associated with an increased incidence of brain metastasis. While selpercatinib...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • In the current case report, authors detail clinical outcomes of a 71-year-old non-smoker with RET-fusion NSCLC who is treated with frontline pembrolizumab. OF note, the patient exhibited brain, Show More
Therapeutic Advances in the Management of Patients with Advanced RET Fusion-Positive Non-Small Cell Lung Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34165651/
Screening for activating driver gene alterations at the time of diagnosis is the standard of care for advanced non-small cell lung cancer (NSCLC). Activating RET fusions are identified in approximately...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • Conclusion/Relevance: “The development of the RET-selective TKIs [tyrosine-kinase inhibitors] selpercatinib and pralsetinib offers patients with RET fusion-positive NSCLC a preferred treatment option with improved clinical efficacy and tolerability. Show More
Efficacy comparison between microwave ablation combined with radiation therapy and radiation therapy alone for locally advanced nonsmall-cell lung cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34269304/
1 Medical Oncology, School of Medicine and Life Sciences, Shandong Academy of Medical Sciences, Jinan University; The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy...