Patient-Reported Outcomes with Selpercatinib Among Patients with RET Fusion-Positive Non-small Cell Lung Cancer in the Phase 1/2 LIBRETTO-001 Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34523767/
Patients with non-small cell lung cancer (NSCLC) generally experience greater symptom burden and lower health-related quality of life (HRQoL) as disease progresses. In a phase 1/2 trial, improvements in HRQoL...
-
NSCLC Connect4yrKey Points • Conclusion/Relevance: “In this interim analysis, the majority of patients with RET fusion-positive NSCLC remained stable or improved on all QLQ-C30 subscales at each study visit, demonstrating the favorable Show More
Methods for actionable gene fusion detection in lung cancer: now and in the future - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34525844/
Although gene fusions occur rarely in non-small-cell lung cancer (NSCLC) patients, they represent a relevant target in treatment decision algorithms. To date, immunohistochemistry and fluorescence in situ hybridization are the...
Real-world evaluation of second line chemotherapy for patients with advanced non-small cell lung cancer harboring preexisting interstitial lung disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34415485/
Twenty-four patients with a median age of 71 years who were treated between April 2013 and March 2021 were included. The response rate after second-line chemotherapy with S-1 (n =...
β-elemene inhibits non-small cell lung cancer cell migration and invasion by inactivating the FAK-Src pathway - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34504549/
Despite sustained effort, the prognosis of lung cancer remains poor and the therapeutic responses are limited. Cell movement ability is a prerequisite for lung cancer metastasis, which involves focal adhesion...
Inhibin βA is an independent prognostic factor that promotes invasion via Hippo signaling in non‑small cell lung cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34505633/
Inhibin βA (INHBA) serves a prognostic and tumor‑promoting role in numerous types of cancer. The present study aimed to determine the clinical significance of INHBA in non‑small cell lung cancer...