Opposite response of lung adenocarcinoma and its choroidal metastases upon ramucirumab plus docetaxel therapy after immunotherapy: a case report - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34591203/

We report a unique case of advanced non-small cell lung cancer that exhibited the opposite response to its unilateral choroidal metastases upon ramucirumab plus docetaxel treatment. A combination of cisplatin,...

Identification of RET fusions in a Chinese multi-cancer retrospective analysis by next-generation sequencing - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34710947/

Fusion of RET with different partner genes has been detected in papillary thyroid, lung, colorectal, pancreatic and breast cancer. Approval of Retevmo (Selpercatinib) for treatment of lung and thyroid cancer...

Selpercatinib for lung and thyroid cancers with RET gene mutations or fusions - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34713870/

Aberrations in oncogene RET (rearranged during transfection) have been found to be the cause of different kinds of malignancies, especially in lung and thyroid cancers. Targeted therapy of RET-altered cancers...

Prognostic Role of Monocytic Myeloid-Derived Suppressor Cells in Advanced Non-Small-Cell Lung Cancer: Relation to Different Hematologic Indices - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34671684/

Mo-MDSCs represent one of the key mechanisms in the immunosuppressive tumor microenvironment (TME) to play major roles not only in the carcinogenesis of lung cancer but also in disease progression...

Body composition and inflammation impact in non-small cell lung cancer patients treated by first-line immunotherapy - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/34670403/

Background: Immunotherapy changed the landscape of non-small cell lung cancer (NSCLC). Efforts were made to implement its action. This study aims to describe body composition, nutritional and inflammatory status in...