Acute Myeloid Leukemia
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The role of computational pathology in predicting expression of selected immunohistochemical markers. - PubMed

The role of computational pathology in predicting expression of selected immunohistochemical markers. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42429431

Discover AI's role in computational pathology, predicting IHC marker expression and addressing pre-analytical challenges in oncology diagnostics.


AI aids computational pathology by predicting IHC marker expression, optimizing workflows, and addressing pre-analytical bottlenecks. Integration depends on platform compatibility. Specialty Focus: Oncology.

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Application and challenges of chimeric antigen receptor T cell therapy in the treatment of acute myeloid leukemia (Review). - PubMed

Application and challenges of chimeric antigen receptor T cell therapy in the treatment of acute myeloid leukemia (Review). - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42383288

Explore CAR-T therapy advancements for AML, addressing obstacles like antigen escape and microenvironment modulation with improved antigen selection and CAR optimization to enhance efficacy.


CAR-T therapy in AML faces challenges like antigen absence and heterogeneity. Advances include improved antigen selection and CAR optimization to overcome these barriers.

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Independent PML::RARA-positive acute promyelocytic leukemia arising during BCR::ABL1-positive chronic myeloid leukemia. - PubMed

Independent PML::RARA-positive acute promyelocytic leukemia arising during BCR::ABL1-positive chronic myeloid leukemia. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/42366058

Explore a rare case of PML::RARA-positive APL in an octogenarian with CML, underscoring thorough cytogenetic and molecular assessments.


This case highlights independent PML::RARA-positive APL in an octogenarian man with CML, intolerant to multiple TKIs, emphasizing integrated evaluation.

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Bilateral Exudative Chorioretinopathy in All-trans Retinoic Acid-Associated Differentiation Syndrome. - PubMed

Bilateral Exudative Chorioretinopathy in All-trans Retinoic Acid-Associated Differentiation Syndrome. - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41115288

In APL treatment, early detection of ocular issues through ophthalmic evaluation may prevent vision loss linked to differentiation syndrome. Specialty Focus: Oncology.


Early detection of bilateral exudative retinal detachment in APL patients on ATRA may prevent vision loss associated with differentiation syndrome. Specialty Focus: Oncology.

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In newly diagnosed AML, what biologic finding most influences your treatment strategy?

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