NSCLC Connect
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Biological Significance of 18 F-FDG PET/CT Maximum Standard Uptake Value for Predicting EGFR Mutation Status in Non-Small Cell Lung Cancer Patients - PubMed

Biological Significance of 18 F-FDG PET/CT Maximum Standard Uptake Value for Predicting EGFR Mutation Status in Non-Small Cell Lung Cancer Patients - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33568935/

doi: 10.2147/IJGM.S287506. 1 Department of Respiratory Medicine, Daping Hospital, Army Medical University, Chongqing, People's Republic of China. 2 Department of Pathology, Daping Hospital, Army Medical University, Chongqing, People's Republic of...

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circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity

circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity

Source : https://www.nature.com/articles/s41467-020-20527-z

Circular RNAs (circRNA) is a class of non-coding RNAs that can regulate gene translation and function. Here the authors show that a circRNA, circNDUFB2, is downregulated in non-small cell lung...

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VPS33B modulates c-Myc/p53/miR-192-3p to target CCNB1 suppressing the growth of non-small cell lung cancer

VPS33B modulates c-Myc/p53/miR-192-3p to target CCNB1 suppressing the growth of non-small cell lung cancer

Source : https://cell.com/molecular-therapy-family/nucleic-acids/retrieve/pii/S2162253120303668?_returnURL=https://linkinghub.elsevier.com/retrieve/pii/S2162253120303668?showall=true

The dysfunction of a large number of genes participates in the pathogenesis of NSCLC. Liu and colleagues demonstrated that VPS33B acts as a tumor suppressor to halt NSCLC pathogenesis and...

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Targeted Therapy in Advanced and Metastatic Non-Small Cell Lung Cancer. An Update on Treatment of the Most Important Actionable Oncogenic Driver Alterations

Targeted Therapy in Advanced and Metastatic Non-Small Cell Lung Cancer. An Update on Treatment of the Most Important Actionable Oncogenic Driver Alterations

Source : https://www.mdpi.com/2072-6694/13/4/804

Due to groundbreaking developments and continuous progress, the treatment of advanced and metastatic non-small cell lung cancer (NSCLC) has become an exciting, but increasingly challenging task. This applies, in particular,...

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Assessment of the Efficacy and Clinical Utility of Different Circulating Tumor Cell (CTC) Detection Assays in Patients with Chemotherapy-Naïve Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Assessment of the Efficacy and Clinical Utility of Different Circulating Tumor Cell (CTC) Detection Assays in Patients with Chemotherapy-Naïve Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Source : https://www.mdpi.com/1422-0067/22/2/925

We herein investigated the detection frequency and clinical relevance of circulating tumor cells (CTCs) in chemotherapy-naïve stage IIIB/IV non-small cell lung cancer (NSCLC), by using the CellSearch and real-time CEACAM5mRNA...