Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion-Positive Lung Cancer by Combining Selpercatinib with Crizotinib - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33082208/

Through the use of SPPs, we were able to offer combination therapy targeting MET -amplified resistance identified on the first-in-human study of selpercatinib. These data suggest that MET dependence is...

A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33769095/

doi: 10.4155/bio-2020-0199. Online ahead of print. 1 CHRU de Tours, Plateforme Recherche, Centre Pilote de Suivi Biologique des Traitements par Anticorps (CePiBAc), Tours, France. 2 Université de Tours, EA4245 Transplantation,...

Meningeal "Lazarus Response" to Lorlatinib in a ROS1-Posit | CMAR

Source : https://www.dovepress.com/meningeal-ldquolazarus-responserdquo-to-lorlatinib-in-a-ros1-positive--peer-reviewed-article-CMAR

Francesco Facchinetti, 1, 2 Antonin Levy, 3, 4 Samy Ammari, 5 Charles Naltet, 6 Pernelle Lavaud, 6 Mihaela Aldea, 6 Damien Vasseur, 7 David Planchard, 6 Benjamin Besse 2, 6...

[Full text] Recognizing Prognostic and Predictive Biomarkers in the Treatment of N | LCTT

Source : https://www.dovepress.com/recognizing-prognostic-and-predictive-biomarkers-in-the-treatment-of-n-peer-reviewed-fulltext-article-LCTT

PD-L1 testing is done through IHC with different assays utilized with various PD-1 or PD-L1 inhibitors; the mechanism of action of these inhibitors in relation to PD-L1 is well described....

Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/33435596/

Lung cancer is one of the most common malignant neoplasms. As a result of the disease's progression, patients may develop metastases to the central nervous system. The prognosis in this...