Liquid Biopsy May Yield Diagnostic, Economic Benefits Over Tissue Biopsy in NSCLC
Liquid biopsy's potential as a diagnostic in cancer is gaining recognition, and its advantages over tissue biopsy in non-small cell lung cancer (NSCLC) were featured in research recently presented at...
Combining radiotherapy with targeted therapies in non-small cell lung cancer: focus on anti-EGFR, anti-ALK and anti-angiogenic agents - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34012812/
The combination of radiotherapy (RT) with targeted agents in non-small cell lung cancer (NSCLC) has been expected to improve the therapeutic ratio and tumor control. The EGFR blockade enhances the...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • In the current study, researchers assessed endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the analysis of epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and programmed death-ligand Show More
Cancer Aneuploidy May Predict Response to Immunotherapy in Patients With NSCLC
Lower levels of cancer aneuploidy were associated with more favorable outcomes after immune checkpoint inhibition in patients with non-small cell lung cancer (NSCLC), according to data presented by Alessi et...
EBUS in optimizing non-small cell lung cancer diagnosis and treatment - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/34013188/
1 Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. 2 Leon Daniello Pulmonology Hospital, Cluj-Napoca, Romania. 3 MEDFUTURE-Research Center for...
Tumor Mutation Burden and Differentially Mutated Genes Among Immune Phenotypes in Patients with Lung Adenocarcinoma - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/33976553/
Low TMB level could be the reason for the poor efficacy of ICBs in patients having EGFR mutation. And mutational frequencies of KRAS and BRCA2 were lower in EGFR -mutant...
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Naveed Saleh, MD, MS – Skipta Team5yrKey Points • In the current study, researchers assessed tumor mutational burden (TMB) and immune phenotype in 223 lung adenocarcinoma (LUAD) patients to elucidate potential mechanisms for poor efficacy of immune Show More
The 'Liquid' Biopsy
Source : https://www.cap.org/member-resources/articles/the-liquid-biopsy
The advent of "precision" medicine is characterized by many new improvements in diagnostic, prognostic, and therapeutic methods and regimens. As part of this initiative, there has been a focus on Show More