Racial Disparities in Cigarette Smoking Behaviors and Differences Stratified by Metropolitan Area of Residence - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35270603/
Our findings show that Black individuals living in non-metropolitan areas do not, in aggregate, have more cigarette smoking exposure relative to White individuals. Additional research is needed to further understand...
Conclusions: Our findings show that Black individuals living in non-metropolitan areas do not, in aggregate, have more cigarette smoking exposure relative to White individuals. Additional research is needed to further understand smoking-related exposures and other factors that may contribute to lung cancer disparities, especially in...
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Albert Dekker4yrthose don't live in urban areas is a completely different population
Artificial Intelligence-Powered Spatial Analysis of Tumor-Infiltrating Lymphocytes as Complementary Biomarker for Immune Checkpoint Inhibition in Non-Small-Cell Lung Cancer - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35271299/
1 Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea. 2 Lunit, Seoul, Republic of Korea. 3 Department of Pathology,...
Conclusion: The AI-powered spatial analysis of TIL correlated with tumor response and progression-free survival of ICI in advanced NSCLC. This is potentially a supplementary biomarker to TPS as determined by a pathologist.
Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also MAPK/JNK signaling pathway
Source : https://www.sciencedirect.com/science/article/abs/pii/S0378874122002057?via=ihub
According to the theory and practice of (TCM), the pathogenesis of traditional Chinese medicine lung carcinoma is associated with many syndromes, such as "sputum stasis", "cough", "lung fever", "lung toxin",...
Conclusion: This study determined the in vivo efficacy of green tea-derived TB on p53-deficient NSCLC (H1299) cells and p53-wild type NSCLC (A549) cells and clarified its p53-independent mechanism mediated by the activation of MAPK/JNK signaling pathway.
Biocatalysis-mediated MOF-to-prussian blue transformation enabling sensitive detection of NSCLC-associated miRNAs with dual-readout signals
Source : https://www.sciencedirect.com/science/article/abs/pii/S0956566322001798?via=ihub
Fe 2+-based MOF can react with K 3[Fe(CN) 6] to yield prussian [email protected] 2+ in situ. * Prussian [email protected] 2+ can arise the temperature readout and electrochemical signal....
Conclusion/Relevance: Under the optimal conditions, using temperature readout or electrochemical readout, miRNA-21 can be detected at concentrations as low as 0.3 fM and 0.32 fM, respectively. Moreover, the developed method is successfully applied to evaluate the expression level of miRNA-21 in serum of NSCLC patients. This work not only...
Characterizing immune-mediated adverse events with durvalumab in patients with unresectable stage III NSCLC: A post-hoc analysis of the PACIFIC trial
Source : https://www.lungcancerjournal.info/article/S0169-5002(22)00043-5/fulltext
Approximately one-third of patients with non-small-cell lung cancer (NSCLC) present with stage III disease at diagnosis, many of whom are inoperable [1]. In patients with unresectable, stage III NSCLC, and...
Conclusion: The risk of imAEs should not deter use of the PACIFIC regimen in eligible patients, as these events are generally well managed through appropriate clinical intervention.
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NSCLC Connect4yrKey Points • Source: Lung Cancer • Conclusion/Relevance: “The risk of imAEs [immune-mediated adverse events] should not deter use of the PACIFIC regimen in eligible patients, as these events are generally well managed through Show More
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NSCLC Connect4yrThanks for sharing, [~Albert--Dekker--adikker@ ] ! Have other specialists encountered immune-mediated adverse effects?